What Differentiates Us?

The NG CELL™ Platform


The NG CELL™ platform is our cutting-edge approach for providing sustained delivery of unparalleled levels of remyelinating and regeneration proteins using the patient’s own stem cells. This technology, in essence, is our proprietary process for identifying, isolating, and enhancing a unique subpopulation of patient-derived bone marrow cells to become remyelinating and neuroregenerative “cellular biofactories” (NG cells). The manufacturing team expands these NG Cells into tens of millions utilizing cGMP and CMC best practices to create injectable doses for patient administration. Each dosing is directly injected into the patient’s spinal cord such that the NG cells can selectively home-in on the damaged area (inflamed lesion sites in the brain and spinal cord) and reside there for up to three months, thereby generating an in-situ sustained secretion of massive amounts of remyelinating, neuronal growth, and repair proteins.


NG-01 is the company’s lead product undergoing clinical trials for treating progressive multiple sclerosis and ALS. NG-01 cells have remyelinating, neuroprotective and neuroregenerative properties. These cells can protect neurons and oligodendrocytes from apoptosis via the release of remyelination, regeneration, and anti-apoptotic molecules (CNTF, BDNF, and others) and have anti-proliferative effects on microglial cells and astrocytes which results in the induction of a neuroprotective microenvironment. In recent studies, NG01 cells have also demonstrated the ability to promote the proliferation and maturation of local neural precursor cells, leading to their differentiation into mature neurons and oligodendrocytes.


NG-02 is our second product which is still under development. In addition to having enhanced neuroprotective and neuroregenerative properties, the NG-02 cells have the potential to differentiate and acquire neuronal cell properties (evidence available from preclinical studies). Intended indications for NG-02 are Parkinson’s disease, Alzheimer’s, and other similar degenerative diseases of the central nervous system.

Dorit Harati

Senior VP Quality and Regulatory Affairs

Dorit Harati brings over 20 years of experience as a Regulatory & Quality Assurance for cell therapy companies in Israel, EU and the US either as a consultant or as a member of the management team. She is an expert on Quality Assurance, Quality Management Systems (QMS), CMC, product development, aseptic and cGMP manufacturing, facility design, cross-continental technology transfer, all in accordance with the EU and FDA regulations.


Before joining Neurogenesis, Dorit was a senior consultant at Dark Horse Consulting Group, a consulting firm that provides comprehensive services to Cell & Gene Therapy companies in the US, EU and Asia. Previously, she has also served as VP Quality Assurance, Manufacturing and Logistics at Gamida Cell, where she established and managed the Quality Assurance, Quality Control, Logistics and Manufacturing Departments, technology transfer to different CROs.

Mark Freedman

Chief Medical and Head of Scientific Advisory Board

Mark Freedman brings more than 30 years of expertise as a leading neurologist and neuroimmunology scientist running therapeutic trials in neurodegenerative diseases. He also has an extensive background in researching the cellular mechanisms behind the immune-mediated demyelination associated with multiple sclerosis.

He holds several prestigious leadership positions, some of which include President of ACTRIMS (Americas Committee for Treatment and Research In Multiple Sclerosis), Director of the Multiple Sclerosis Research Unit (Neurology) at the Ottawa Hospital General Center, and Professor of Medicine (Neurology) at the University of Ottawa.

Nir Netzer

Chief Operating Officer

Dr. Netzer served for over 15 years in cell therapy companies in Israel and in the US as a member of the management team. He is an expert in Stem Cell R&D and operations and in establishing a global strategy for product development, manufacturing, and supply chain, with a clear focus on market viability. Before joining NeuroGenesis, Dr. Netzer served as the VP CMC and Operations at Cell

Cure Neurosciences, acquired by Lineage Cell Therapeutics, Inc. (NYSE American and TASE: LCTX), where he led the development of a novel ‘Thaw- and-Inject’ cell product and the building of Lineage’s state of the art GMP manufacturing facility. Previously, Dr. Netzer was the Research Manager at Pluristem Therapeutics Inc. (NASDAQ: PSTI), where he led the preclinical trials and the finding of the first cell therapy product for treating radiation syndrome following nuclear disasters. Dr. Netzer was a Post-Doctoral fellow in cell biology and viral immunology at the NIAID, NIH and holds a PhD in Biotechnology and immunology from the Technion in Israel.

Ibrahim Kassis

Co-Founder and Chief Technology Officer

Dr. Kassis is one of the world’s experts in Regenerative Medicine and stem-cells based technologies, and production of clinical-grade stem cells for treating multiple sclerosis andamyotrophic lateral sclerosis patients. Dr. Kassis has over 20 years of experience in developing innovative cellular therapies from bench to patient bedside. Dr. Kassis serves as a Senior Scientist at the Department of Neurology, Hadassah Medical Center. Dr. Kassis has published over 30 publications in prestigious peer reviewed publications.

Dimitrios Karussis

Co-Founder and Chief Scientific Officer

Dr. Karussis is considered one the world experts in clinical applications of Stem Cells in Neurological diseases, he is the director of MS Center and department of Neuroimmunology, Cell Therapies at Hadassah Medical Center, Jerusalem (since 2007). Dr. Karussis servers on many editorial boards including the International Multiple Sclerosis, Journal of Neurological Sciences, World Journal of Neurology and others. Dr. Karussis has participated in numerous scientific committees at ECTRIMS, EFNS, ISNI and the European School of Neuroimmunology. Dr. Karussis also serves as the president of the Israeli Neuroimmunology Society (since 2010) and has published over 120 peer-reviewed scientific papers mainly in the field of Stem Cells and Neuroimmunology.

Tal Gilat

Co-Founder and Chief Executive Officer

An accomplished senior executive with over 16 years of CEO experience in public and private companies in Tel Aviv, New York and Silicon Valley. Established and directly managed global high growth sales, business development organizations in North America, Europe and Asia (direct Sales, Inside Sales, One Tier, Two-Tiered Distribution, OEM, IP Licensing etc.).

CEO of AppDome, a recognized market leader in mobile integration as a service (security, connectivity, mobility). Recognized by CIO magazine as one of 2015’s Top 10 Mobility CEOs as well as a 2015 Top Mobile Innovator by the Channel Company. President and CEO of INKSURE Technologies, the industry leader in cloud-based mobile product authentication. Winner of the 2011 Prestigious ID People Americas Award, the Oscars of the ID Industry, for his contribution to the high-security authentication market. Proven track record in the software, hardware industry of increasing top and bottom-line results, previously heading SanDisk Enterprise (NASDAQ: SNDK) in North America and M-System (NASDAQ: FLSH) Enterprise business. In 2000, founded and served as CEO of Kavado Inc. (acquired by Protegrity Inc.), a global web security solutions provider.

Tal holds an MBA from Columbia Business School in New York and a BA with honors in Economics, Business Administration from the Hebrew University in Jerusalem.